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Health Sciences
More cancers may be treated with drugs than previously believed
Using a Penn-designed neural network called PocketMiner, a Penn Medicine research team has identified hidden protein pockets that can provide new opportunities for cancer drugs to bind to.
Pregnancy complications tied to higher risk of death as long as 50 years later
Even decades after delivering pre-term or with conditions like gestational diabetes or high blood pressure, those with complications in pregnancy or birth have a higher risk of death.
How have women in the workforce fared, three years into the pandemic?
Despite hopeful signs that this demographic is returning to work, certain female-dominated sectors, like the care economy, still haven’t recovered, signaling there’s more to learn about COVID-19’s full effect.
A potential strategy to improve T cell therapy in solid tumors
A new Penn Medicine preclinical study finds that a new simultaneous “knockout” of two inflammatory regulators boosted T cell expansion to attach solid tumors.
With frank text and bold illustrations, graphic novel tackles puberty head on
The new book, for 9- to 14-year-olds and written by two Penn undergrads and an alum, details what physically happens in the body as girls experience puberty, plus the internal emotions and external social forces that accompany it.
What drives transplant waitlisting disparities?
For transplant patients, psychosocial evaluations, like other measures in the transplant process, can lead to people of color facing worse outcomes.
The immune system does battle in the intestines to keep bacteria in check
New research from Penn’s School of Veterinary Medicine demonstrates that Yersinia pseudotuberculosis, a relative of the bacterial pathogen that causes plague, triggers the body’s immune system to form lesions in the intestines called granulomas.
States with high COVID-19 death rates also saw high mortality from other causes
Research from Penn, Boston University, and the Robert Wood Johnson Foundation shows that between March 2020 and February 2021 non-COVID deaths accounted for some 20% of excess mortality.
Can we intercept cancer?
Penn researchers are developing new ways to detect and “intercept” cancer from every angle, including basic science to understand the molecular changes that lead to cancer and developing new methods for finding it.
Genomics reveals a complex human history in Africa
An international team of researchers led by Penn geneticists sequenced the genomes of 180 indigenous Africans. The results shed light on the origin of modern humans, African population history, and local adaptation.
In the News
Fentanyl overdoses hit a surprising group of San Franciscans: the city’s dogs
Cynthia Otto of the School of Veterinary Medicine says that fentanyl can be absorbed across the mucous membranes in canine noses, causing dogs to face a life-threatening overdose.
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Rural jails turn to community health workers to help the newly released succeed
According to Aditi Vasan of the Leonard Davis Institute and Perelman School of Medicine, evidence is mounting in favor of the model of training community health workers to help their neighbors connect to government and health care services.
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When it’s time for an aging driver to hit the brakes
Lauren Massimo of the School of Nursing says that losing the ability to drive is a major and dehumanizing loss for older adults.
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What is food noise and how do you get rid of it?
According to Thomas Wadden of the Perelman School of Medicine, people taking GLP-1 drugs are finding that daily experiences that used to trigger a compulsion to eat or think about food no longer have that effect.
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UPenn hosts free online panel for LGBTQ+ workplace inclusion
The Eidos LGBTQ+ Health Initiative, led by José Bauermeister and Jessica Halem of the School of Nursing, will host a free online panel in April on the integration of LGBTQ+ people in the workforce.
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