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Biology
Landscape and climate factors can predict prevalence of Lyme disease bacteria
Environmental models, developed by biologist Dustin Brisson of the School of Arts & Sciences, former graduate student Tam Tran, and colleagues, could help forecast disease hotspots.
T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response
Blocking this process, known as trogocytosis, improved the ability of a CAR T cell therapy to treat cancer in mice, according to research led by School of Veterinary Medicine scientists.
Undergraduates help songbird research project take flight
Through the PURM internship program, Julia Youngman and Eric Tao had the opportunity to work in neuroethologist Marc Schmidt’s lab studying the neural basis of courtship behaviors in songbirds.
Cancer cells selectively load ‘drones’ to keep T cells from infiltrating tumors
Biologist Wei Guo and colleagues elucidate the process of sorting and loading cargo for these biological drones with implications for a more targeted and effective use of checkpoint inhibitor drugs in cancer treatment.
Goodbye to an iconic tree
More than a century old, the American elm located in the heart of the Quadrangle residences has been ailing and is due to be removed the week of July 25. The site will be replanted at a later date with three native white oaks.
Inspired by nature, artificial microtubules can work against a current to transport tiny cargoes
Technology developed by Arnold Mathijssen of the School of Arts & Sciences and colleagues could one day clear blockages in blood vessels or precisely target chemotherapy drugs to a tumor.
Educating community-oriented biologists
Mecky Pohlschröder of the School of Arts & Sciences reflects on an SNF Paideia course that connects research conducted in the STEM field to the broader community, allowing students to observe the influences of their work outside of the lab.
A newly identified stem cell regulator enables lifelong sperm production
Research led by Jeremy Wang of the School of Veterinary Medicine has discovered that the enzyme DOT1L, a stem cell renewal factor, is essential for mice to produce sperm throughout their adult lives.
A $365 million development will expand the life sciences hub at Pennovation Works
Penn Senior Executive Vice President Craig Carnaroli speaks with Penn Today about the evolution of the research and manufacturing project, led by Longfellow Real Estate Developers, and its value for Penn and the region.
How bacteria store information to kill viruses (but not themselves)
Researchers from the School of Arts & Sciences have discovered that the balance between fighting viruses and avoiding autoimmunity has a key role in shaping how bacteria “remember” old infections.
In the News
Bird flu virus has been spreading in U.S. cows for months, RNA reveals
Louise Moncla of the Veterinary School of Medicine says that the bird flu virus is clearly being transmitted to cows in some way.
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Man does DNA test, not prepared for what comes back ‘unusually high’
César de la Fuente of the School of Engineering and Applied Science and Perelman School of Medicine says that Neanderthal DNA provides insights into human evolution, population dynamics, and genetic adaptations, including correlations with traits such as immunity and susceptibility to diseases.
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When is the best time to take L-theanine—morning or night?
According to Colleen Tewksbury of the School of Nursing, research suggests that L-theanine may help support stress management, sleep, and potentially weight management.
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Is the flu shot market a slam dunk for mRNA vaccines? Experts aren’t so sure
Scott Hensley of the Perelman School of Medicine is working on a flu vaccine to provide protection against 20 subtypes of flu that may pose a pandemic threat in the future.
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Thanks, Neanderthals: How our ancient relatives could help find new antibiotics
A study by César de la Fuente of the Perelman School of Medicine and colleagues used AI to recreate molecules from ancient humans that could be potential candidates for antimicrobial treatments.
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Long COVID brain fog may originate in a surprising place, say scientists
A study by Christoph Thaiss and Maayan Levy of the Perelman School of Medicine and colleagues finds that long COVID’s neurological symptoms, like brain fog, memory loss, and fatigue, may stem from serotonin reduction.
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