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Perelman School of Medicine
More than skin deep: A molecular and mechanistic look at pigmentation variation
More than skin deep: A molecular and mechanistic look at pigmentation variation
A new collaborative study offers a better understanding of genes and variants responsible for skin color, providing insights into human evolution and local adaptation.
Out-of-pocket cost increase could put HIV prevention medications out of reach
Out-of-pocket cost increase could put HIV prevention medications out of reach
A Penn Medicine study finds that even modest increases in out-of-pocket costs for HIV prevention drugs could double the rate at which prescriptions go unfilled.
New AI tool brings precision pathology for cancer into quicker, sharper focus
New AI tool brings precision pathology for cancer into quicker, sharper focus
Researchers at Penn Medicine have developed an artificial intelligence tool to quickly analyze gene activities in medical images and provide single-cell insight into diseases in tissues and tissue microenvironments.
How Penn Medicine is changing the world with mRNA
How Penn Medicine is changing the world with mRNA
Vaccines are just the beginning of the potential for messenger RNA, the Nobel Prize-winning technology.
New treatment reverses Alzheimer’s disease signs
New treatment reverses Alzheimer’s disease signs
According to a preclinical study from Penn Medicine researchers, a molecular compound mimics the effect of natural chaperones that are depleted in the aging brain.
Penn Medicine sets a worldwide record with 100 kidney paired donation transplants in a year
Penn Medicine sets a worldwide record with 100 kidney paired donation transplants in a year
The Penn Transplant Institute coordinates with the National Kidney Register to help pair the more than 90,000 patients on the waitlist with a deceased donor.
Research shows how stress activates neurons that disrupt sleep
Research shows how stress activates neurons that disrupt sleep
New research from Penn Medicine shows suppressing these neurons may be a promising target for therapies to treat stress-related sleep disorders, like insomnia and PTSD.
First in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses
First in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses
The therapy tested in a Phase 1 clinical trial might drastically change the way the T cells work, potentially allowing the new CAR T cell product to work where other products have failed.
One in six patients with opioid use disorder leaving the hospital before completing treatment
One in six patients with opioid use disorder leaving the hospital before completing treatment
A new Penn Medicine analysis shows that discharges too early for patients with opioid use disorder increased over 50% between 2016 and 2020.
Could a single shot heal heart disease?
Could a single shot heal heart disease?
Experts at Penn Medicine are researching novel treatments for heart disease, including CRISPR gene editing technology, CAR T technology, and mRNA injections.
In the News
Philadelphia Inquirer
Inside Penn’s transfer center
Penn Medicine’s transfer command center gets patients from affiliated hospitals and hospitals outside Philadelphia to specialized care that can save lives, with comments from CEO Kevin Mahoney.
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Philadelphia Inquirer
Operating rooms are major sources of greenhouse gasses. Penn is eliminating a form of anesthesia that hangs in the air for more than a decade after use
Penn Medicine is phasing out the anesthesia desflurane at four of its six hospitals to eliminate harmful greenhouse gases, with remarks from Greg Evans.
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Philadelphia Inquirer
Broad Street runners from Penn are racing with gyroscopes to study the Achilles tendon
Casey Jo Humbyrd and Josh Baxter of the Perelman School of Medicine and colleagues will track data from running the Broad Street Run to understand how a healthy Achilles tendon functions.
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National Geographic
What is topical steroid withdrawal? If you have eczema, here’s what you should know
Bruce Brod of the Perelman School of Medicine says that prolonged or overuse of topical steroids can cause rosacea, skin thinning, stretch marks, and an extreme and debilitating withdrawal.
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Fox 29 (Philadelphia)
Cannabis reclassification could be game-changer for U.S. drug policy
Michael Cirigliano of the Perelman School of Medicine says that marijuana deserves to be removed from the same category as LSD, heroin, and fentanyl.
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