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Perelman School of Medicine
Genetic switch turns tumor suppressor into oncogene in colorectal cancer
Genetic switch turns tumor suppressor into oncogene in colorectal cancer
Researchers from the School of Veterinary Medicine have shown that an enzyme that suppresses early-stage colorectal cancer switches to become an oncogene as the cancer progresses.
A link between memory and appetite in the brain to explain obesity
A link between memory and appetite in the brain to explain obesity
Penn Medicine researchers have found the hippocampal subnetwork, located within the memory center of the brain, is more dysregulated in patients with higher body mass indexes, leading to an inability to control or regulate eating habits.
An immunotherapy strategy against all blood cancers
An immunotherapy strategy against all blood cancers
Researchers at Penn Medicine have demonstrated a new potential treatment using CAR T cell therapy using a CRISPR base-editing to develop a method called “epitope editing.”
A summer studying the aesthetic brain
A summer studying the aesthetic brain
For third-year Olivia Kim, a PURM research experience with Penn neuroscientist Anjan Chatterjee allowed her to combine her love of neuroscience and art in a working lab.
Trading decisions are observable in the eyes of buyers and sellers
Trading decisions are observable in the eyes of buyers and sellers
In a new collaborative study, PIK Professor Michael Platt models how the decision-making process unfolds in the brains of buyers and sellers considering a deal. These decisions were observable in eye movements and pupil dilation.
Carl June on the boundless potential of CAR T cell therapy
Carl June on the boundless potential of CAR T cell therapy
In a Q & A, June, the Richard W. Vague Professor in Immunotherapy, and Daniel Baker, a fourth-year doctoral student in Penn’s Cell and Molecular Biology department, discuss how the treatment can extend to treating diseases beyond cancer.
Chasing the mysteries of microbiome communication in our bodies
Chasing the mysteries of microbiome communication in our bodies
Penn Medicine’s Maayan Levy and Christoph Thaiss, both assistant professors of microbiology, pursue an understanding of the the microbiome, the entirety of microbial organisms associated with the human body, and its relation to fundamental bodily systems.
For a new generation of antibiotics, scientists are bringing extinct molecules back to life
For a new generation of antibiotics, scientists are bringing extinct molecules back to life
Marrying artificial intelligence with advanced experimental methods, Penn Engineering’s Machine Biology Group has mined the ancient past for future medical breakthroughs, bringing extinct molecules back to life.
SCALAR: A microchip designed to transform the production of mRNA therapeutics and vaccines
SCALAR: A microchip designed to transform the production of mRNA therapeutics and vaccines
Researchers have developed a platform that could rapidly accelerate the development of mRNA-based lipid nanoparticle vaccines and therapeutics at both the small and largescale, SCALAR.
Hard at work, crews make progress during summer construction
Hard at work, crews make progress during summer construction
Ahead of the arrival of students, summer on campus bustles with construction teams advancing various building projects and maintenance work. Here, a look at what’s happening now.
In the News
Slate.com
What’s going on with tranq?
Jeanmarie Perron of the Perelman School of Medicine says that the appearance and progression of skin ulcers and tissue loss on xylazine users is different than with other intravenous drugs.
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The Hill
It’s time to end the Medicare-Medicaid merry-go-round
In an opinion essay, Rachel M. Werner of the Leonard Davis Institute, Wharton School, and Perelman School of Medicine says that Medicare and Medicaid fail to integrate coverage and coordinate care across their two plans.
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Philadelphia Inquirer
Inside Penn’s transfer center
Penn Medicine’s transfer command center gets patients from affiliated hospitals and hospitals outside Philadelphia to specialized care that can save lives, with comments from CEO Kevin Mahoney.
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Philadelphia Inquirer
Operating rooms are major sources of greenhouse gasses. Penn is eliminating a form of anesthesia that hangs in the air for more than a decade after use
Penn Medicine is phasing out the anesthesia desflurane at four of its six hospitals to eliminate harmful greenhouse gases, with remarks from Greg Evans.
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Philadelphia Inquirer
Broad Street runners from Penn are racing with gyroscopes to study the Achilles tendon
Casey Jo Humbyrd and Josh Baxter of the Perelman School of Medicine and colleagues will track data from running the Broad Street Run to understand how a healthy Achilles tendon functions.
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