A cellular protein called HDAC6, newly characterized as a gatekeeper of steroid biology in the brain, may provide a novel target for treating and preventing stress-linked disorders, such as depression and post-traumatic stress disorder (PTSD), according to research from the Perelman School of Medicine at the University of Pennsylvania.
PHILADELPHIA -- Protein design is technique that is increasingly valuable to a variety of fields, from biochemistry to therapeutics to materials engineering. University of Pennsylvania chemists have taken this kind of design a step further; using computational methods, they have created the first custom-designed protein crystal.
Arthur Caplan of the Perelman School of Medicine says, “Drug companies … don’t want a death attributed to their new drug.”
Garret FitzGerald, MD, chair of the Department of Pharmacology and Director of the Institute for Translational Medicine & Therapeutics, Perelman School of Medicine at the University of Pennsylvania, is among the 44 newly elected Fellows and eight newly elected Foreign Members to the Royal Society.
Penn Field Center for Children’s Policy, Practice & Research: “Can America Stop Hurting Its Children?”
PHILADELPHIA – At its April 24 Spring 2012 Community Symposium, the Field Center for Children’s Policy, Practice & Research at the University of Pennsylvania poses the question, “Can America Stop Hurting its Children?”
The Symposium will be from 8:30 to 10:30 a.m. at the Levy Conference Center at the Penn Law School, 34th and Chestnut streets.
Early Treatment Improves Outcomes in Rare, Often Undiagnosed Form of Encephalitis, Penn Researchers Find
A mysterious, difficult-to-diagnose, and potentially deadly disease that was only recently discovered can be controlled most effectively if treatment is started within the first month that symptoms occur, according to a new report by researchers from the Perelman School of Medicine at the University of Pennsylvania.
Two new studies analyzing treatment decisions in late-stage amyotrophic lateral sclerosis (ALS) patients shed light onto treatments aimed to extend the duration and quality of life in this progressively debilitating neuromuscular disorder. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that waiting until the last minute to receive one treatment resulted in not living long enough to experience the benefits.
Teasing out the exact type or types of dementia someone suffers from is no easy task; neurodegenerative brain diseases share common pathology and often co-occur. Researchers from the Perelman School of Medicine at the University of Pennsylvania are continuing efforts to differentiate diseases, such as Alzheimer's disease (AD) from frontotemporal lobar degeneration (FTLD), as FTLD is often clinically difficult to distinguish from atypical presentations of AD.
Crew teams at dawn. A midday rush to food trucks along Spruce Street. An evening performance in an on-campus theater.
These are just a handful of the moments, big and small, captured in the first-ever University-wide photo project, “A Day in the Life of Penn.”