Lead Poisoning in Pa., N.J. May Be Worse Than Flint

February 5, 2016

Marilyn Howarth of the Perelman School of Medicine comments on lead poisoning in the Pennsylvania and New Jersey region.

Article Source: Philly.com

Circadian Clock and Aging

February 3, 2016

Garrett FitzGerald of the Perelman School of Medicine is quoted about studying the role of the internal clock in human disease.

Article Source: The-Scientist.com

How Wing Bowl Contestants Eat 20 Pounds of Chicken in 30 Minutes

February 4, 2016

Marc Levine of the Perelman School of Medicine is quoted about how speed eaters manage to eat as much as they do and how quickly.

Article Source: PhillyVoice.com
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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194February 4, 2016

Two Penn Professors Call Attention to the Use of Race in Human Genetic Research

Two University of Pennsylvania professors are coauthors, along with two other scholars, on a perspective piece published this week in the journal Science that calls for an end to the use of genetic concepts of race in biological research.

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Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658February 3, 2016

Penn Study Prompts Reevaluation of Assumptions on Role of Internal Clock in Human Disease

Abolishing the 24-hour clock by knocking out a key gene during development accelerates aging and shortens lifespan by two thirds in mice, but this effect is absent if the gene deletion is delayed until after birth, according to a new study published this week in Science Translational Medicine by scientists from the Perelman School of Medicine at the University of Pennsylvania.

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Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658February 2, 2016

"Gene Fusion" Mutation Uses Three-Way Mechanism To Drive Childhood Brain Cancers

A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists from the Perelman School of Medicine

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Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658February 2, 2016

Penn Study Identifies Enzyme Key to Link Between Age-Related Inflammation and Cancer

For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Inhibitors of the enzyme are being developed as a new anti-cancer target.

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Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658February 1, 2016

Viral Gene Editing System Corrects Genetic Liver Disease in Newborn Mice

For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected. Delivery of the vector to newborn mice improved their survival while treatment of adult animals, unexpectedly, made them worse, according to a new study by investigators from the Perelman School of Medicine at the University of Pennsylvania The team published their findings this week in Nature Biotechnology.

Video: New Penn Medicine Video Provides Incredible, Personal Look at Post-mastectomy Nipple Tattoos

February 1, 2016

Joseph Serletti and Mandy Sauler of Penn Medicine are featured in a video about nipple reconstruction and medical tattooing for post-mastectomy patients.

Article Source: Philadelphia Magazine
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Media Contact:Michele Berger | mwberger@upenn.edu | 215-898-6751February 2, 2016

Penn Researchers Offer New Approach to Treating Cocaine Addiction

blurb: 
University of Pennsylvania researchers Heath Schmidt, Matthew Hayes and Bart De Jonghe have shown that a drug used for diabetes and obesity may also reduce cocaine dependence.

In the ongoing fight against drug addiction, researchers from the University of Pennsylvania’s School of Nursing and Perelman School of Medicine have discovered a unique application for an FDA-approved drug curr