Bioengineering

Nanoparticles can turn off genes in bone marrow

Using specialized nanoparticles, researchers from Penn Engineering and MIT have developed a way to turn off specific genes in cells of bone marrow, which play an important role in producing blood cells. 

From Penn Engineering Today

Computer-generated antibiotics and biosensor Band-Aids

For Penn synthetic biologist César de la Fuente and his team, these concepts aren’t some far-off ideal. They’re projects already in progress, and they have huge real-world implications should they succeed.

Michele W. Berger



In the News


The New York Times

Can your personal medical devices be recycled?

A lab at the School of Engineering and Applied Science led the development of a COVID test made from bacterial cellulose, an organic compound.

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Science Alert

Scientists think they’re on the verge of breaching the blood-brain barrier

Michael Mitchell of the School of Engineering and Applied Science and colleagues have constructed a model that could potentially allow drug transporters to bypass the blood-brain barrier.

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Popular Mechanics

How severed cockroach legs could help us ‘fully rebuild’ human bodies

David Meaney of the School of Engineering and Applied Science oversees an undergraduate bioengineering lab that uses cockroach legs to teach students to work with human prostheses.

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United Press International

Herniated discs could be repaired with biologic patch one day, researchers say

Preclinical research by Robert Mauck of the Perelman School of Medicine, Thomas Schaer of the School of Veterinary Medicine, and Ana Peredo, a Ph.D. graduate of the School of Engineering and Applied Science, reveals how a biologic patch activated by natural motion could become a key tool for repairing herniated discs in the back and relieving pain.

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NPR

Thanks, Neanderthals: How our ancient relatives could help find new antibiotics

A study by César de la Fuente of the Perelman School of Medicine and colleagues used AI to recreate molecules from ancient humans that could be potential candidates for antimicrobial treatments.

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New York Post

Why CAR T cell therapy is the cancer killer the world needs now

Research from Michael Mitchell of the School of Engineering and Applied Science has developed a new method to stop cytokine release during CAR T cell therapy, preventing some of its more dangerous side effects.

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