Penn Medicine: Donor Smoking and Recipient Obesity Tied to Higher Rates of Death and Lung Injury After Lung Transplantation
March 6, 2013
PHILADELPHIA — A multi-institution study led by researchers at the Perelman School of Medicine at the University of Pennsylvania has identified several important risk factors, including a donor’s smoking history and recipient obesity, linked to severe primary graft dysfunction (PGD), the major cause of serious illness and death after lung transplantation. PGD is a common complication that affects up to 25 percent of lung transplant patients shortly after surgery. The study also found that some previously identified risk factors, including donor sex, race, age, and means of death, were not associated with PGD.