Displaying 61 - 70 of 876 articles
Penn Researchers Engineer Macrophages to Engulf Cancer Cells in Solid Tumors
July 6, 2017
One reason cancer is so difficult to treat is that it avoids detection by the body. Agents of the immune system are constantly checking the surfaces of cells for chemical signals that say they belong, but cancer cells express the same chemical signals as healthy ones. Without a way for the immune system to tell the difference, little stands in the way of cancer taking over.
A Perturbed Skin Microbiome Can Be ‘Contagious’ and Promote Inflammation, Penn Study Finds
June 29, 2017
Even in healthy individuals, the skin plays host to a menagerie of bacteria, fungi and viruses. Growing scientific evidence suggests that this lively community, collectively known as the skin microbiome, serves an important role in healing, allergies, inflammatory responses and protection from infection.
Penn Study Details Impact of Antibiotics, Antiseptics on Skin Microbiomes
June 19, 2017
The use of topical antibiotics can dramatically alter communities of bacteria that live on the skin, while the use of antiseptics has a much smaller, less durable impact. The study, conducted in mice in the laboratory of Elizabeth Grice, PhD, an assistant professor of Dermatology in the Perelman School of Medicine at the University of Pennsylvania, is the first to show the long-term effects of antimicrobial drugs on the skin microbiome. Researchers published their findings today in the journal Antimicrobial Agents and Chemotherapy.
Penn/CHOP Team Gains Insights Into Cause of Infant Leukemias and Those Triggered by Chemotherapy
June 14, 2017
Certain pediatric leukemias share a common underlying cause with treatment-related secondary leukemias. Both diseases involve translocations in the KMT2A gene, in which a portion of this gene is swapped out with DNA from a “partner” gene on a separate chromosome. The resulting recombination causes an abnormal genetic rearrangement called a translocation that leads to leukemia, which is cancer of the blood cells. Patients with these types of leukemias tend to have poor outcomes.
Pediatric Nurses Miss Necessary Care More Often in Poor Work Environments, Penn Study Finds
June 13, 2017
In a new study, researchers at the University of Pennsylvania School of Nursing’s Center for Health Outcomes and Policy Research and the Children’s Hospital of Philadelphia found that pediatric nurses with poor work environments and higher patient loads are more likely to miss required care.
Robert Wood Johnson Foundation Grant Creates New Fellowships for the University of Pennsylvania’s Penn Futures Project
June 9, 2017
The University of Pennsylvania will establish the Calvin Bland Faculty Fellowships for the Penn Futures Project. A $2 million endowment from the Robert Wood Johnson Foundation will create a separate fellowship for each school in Penn Futures: the School of Nursing, Graduate School of Education and School of Social Policy & Practice.
Two Types of Empathy Elicit Different Health Effects, Penn Psychologist Shows
May 24, 2017
When a close friend shares bad news, our instinct is to help. But putting ourselves in a friend’s shoes, imagining how we would feel if we were the one suffering, may have detrimental effects on our own health, according to a new study led by the University of Pennsylvania’s Anneke E. K. Buffone. She is the lead research scientist of the World Well-Being Project in the School of Arts & Sciences’ Positive Psychology Center.
Penn Researchers Receive $9.25M Grant from the Paul G. Allen Family Foundation to Study Cellular Mechanisms of Concussion and Ways to Improve Recovery
May 19, 2017
The Paul G. Allen Family Foundation announced today it has awarded a $9.25 million grant to Penn researchers to study the underlying mechanisms of concussion and help uncover potential clinical interventions that could improve recovery.
Penn/CHOP Study Will Translate Objective Diagnostic Measures for Sports-related Concussion Across the Lab, Clinic and Field
May 18, 2017
How can physicians and engineers help design athletic equipment and diagnostic tools to better protect teenaged athletes from concussions? A unique group of researchers with neuroscience, bioengineering and clinical expertise are teaming up to translate preclinical research and human studies into better diagnostic tools for the clinic and the sidelines as well as creating the foundation for better headgear and other protective equipment.
Penn Psychologist Finds Friendship Group Influences Dating Violence Risk for Early-maturing Girls
May 17, 2017
Girls who go through puberty and develop physically earlier than their peers are at risk of low self-esteem as well as emotional and behavioral problems. Research has also indicated that they are at a heightened risk of experiencing physical or sexual violence.