Medicine

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Penn’s Ezekiel Emanuel Named $1M 2018 Dan David Prize Laureate
February 7, 2018
Globally renowned bioethicist Ezekiel J. Emanuel, the University of Pennsylvania’s Vice Provost of Global Initiatives and Chair of the Department of Medical Ethics and Health Policy in the Perelman School of Medicine at Penn, has been named a 2018 Dan David Prize Laureate. Emanuel will receive the award at the Dan David Prize Award Ceremony May 6, at Tel Aviv University, Israel.
Penn Researchers Prove That Precisely Timed Brain Stimulation Improves Memory
February 6, 2018
The Restoring Active Memory program, led by Michael Kahana of the School of Arts and Sciences, is one step closer to its goal of creating a fully implantable neural monitoring and stimulation system. The team, which includes researcher Youssef Ezzyat, has shown that precisely timed electrical stimulation to the left side of the brain can reliably and significantly enhance learning and memory performance by as much as 15 percent.
Penn Vet Study Uncovers Therapeutic Targets for Aggressive Triple-negative Breast Cancers
February 2, 2018
As part of a breast-cancer diagnosis, doctors analyze the tumor to determine which therapies might best attack the malignancy. But for patients whose cancer is triple-negative — that is, lacking receptors for estrogen, progesterone and Her2 — the options for treatment dwindle. Triple-negative cancers, or TNBC, also tend to be more aggressive than other cancer subtypes.
Dating Partners More Violent and Account for More Domestic Violence Than Spouses
January 30, 2018
More than 80 percent of intimate partner violence reported to Philadelphia police involves current and former boyfriends and girlfriends, according to research from Susan B. Sorenson of the School of Social Policy & Practice. That’s much higher than married partners: Current and ex-spouses account for less than 15 percent and 4 percent, respectively.
Penn Engineers Make First Full Network Model of the Musculoskeletal System
January 18, 2018
Network science examines how the actions of a system’s individual parts affect the behavior of the system as a whole. Some commonly studied networks include computer chip components and social media users, but University of Pennsylvania engineers are now applying network science to a much older system: the human body.
Improvements in Mortality Rates Are Slowed by Rise in Obesity in the United States
January 15, 2018
With countless medical advances and efforts to curb smoking, one might expect that life expectancy in the United States would improve. Yet according to recent studies, there’s been a reduction in the rate of improvement in American mortality during the past three decades. According to a new study published in the Proceedings of the National Academy of Sciences, a rise in obesity is to blame.
By Altering Bone Marrow, ‘Training’ Can Prepare Innate Immune System for Future Challenges
January 11, 2018
When you receive a vaccine against a disease like polio or influenza, your immune system gears up to defend against that particular infection. If you wind up getting chickenpox instead, or even a slightly different strain of the flu, you would be out of luck. That’s because traditional vaccines enlist the adaptive immune system, the functions of which are carried out largely by hyperspecific T and B cells, each targeted to a particular threat.
Weekly Fish Consumption Linked to Better Sleep, Higher IQ, Penn Study Finds
December 21, 2017
Regular fish consumption has been shown to improve cognition. It’s also been known to help with sleep. A new study, conducted by Jianghong Liu, Jennifer Pinto-Martin and Alexandra Hanlon of the School of Nursing and PIK Professor Adrian Raine, connects all three for the first time. The research team found that children who eat fish at least once a week sleep better and have higher IQs by an average of 4 points.
Commonalities in Late Stages of Different Inherited Blinding Diseases Suggest Targets for Therapy
December 20, 2017
Gene therapy holds promise for treating a variety of diseases, including some inherited blinding conditions. But for a gene therapy to be effective, one must know the precise gene responsible for a given individual’s disorder and develop a tailored treatment. For diseases that may be caused by mutations in many different genes, developing individual gene therapy approaches can be prohibitively costly and time-intensive to pursue.
LGBQ Adolescents at Much Greater Risk of Suicide than Heterosexual Counterparts
December 19, 2017
In the Journal of the American Medical Association, May Wharton graduate Theodore L. Caputi published findings showing that adolescents who identify as gay, lesbian, bisexual or questioning are much more likely to consider, plan or attempt suicide than their heterosexual peers. Though similar conclusions have been reported, Caputi and colleagues used a unique methodology that updates the findings in a new way.

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